Can you try resetting your Meconfig.db file. The following post will tell you how to locate it. Then, after closing Multi-Edit (ME), rename the file to something like Meconfig-bak.db. Then restart ME and see if the problem persists. If the problem persists, you can rename the file back (with ME not running) and we will try something else.
Here is the postviewtopic.php?t=2013